SENSORY NEURONS AND PAIN

Both pain and inflammation are under the control of specific aspects of the nervous system. Medical efforts to therapeutically affect both conditions are major and continuous, as well as central to medical therapeutics.

 

Present strategies such as anti-inflammatory drugs and analgesics (both topical and systemic) are relatively ineffective and seek to influence pathological processes after they have reached clinical need.

 

It has been realized that both processes primarily involve 'nociceptors' such as TRPV1 (sensory neurons). Rescuderm interacts with these nociceptors on our body to mitigate pain sensation and prevent cell-damage.

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Nociceptors like TRPV1 are highly specialized nerve fibers and receptors that translate trauma, be it a heavy tan or stove-top burn, into pro-inflammatory lesions and pain. Nociceptors direct the development of pain perception, but in addition, they trigger and amplify secondary responses to the noxious insults they sense.

 

This amplification includes inflammation, and irritation. The latter is greatly reduced by Rescuderm, explaining the distinct acceleration of tissue healing (less tissue damage means less healing required as well as faster healing).

 

The broad antimicrobial effectiveness of the formulation, which has been demonstrated and accepted by Health Canada, aids in that process.

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The NociPharm Genetics' research program was directed by Dr. H Michael Dosch (Senior Scientist, SickKids) and executed through specific research contracts placed with qualified research laboratories. Contact for more details.

 

RESEARCHED AND PROVEN

The Rescuderm formulation used in both tube variations has been studied for over a decade in top research institutes across Canada, giving concrete evidence that it is effective.

 

In the University of Guelph, Dr. Dosch’s Laboratory at SickKids (Toronto, Canada) and Defense Research & Development Canada (the premier burns & trauma research institute of the Canadian Military), it was shown that Rescuderm outperformed all possible expectations.

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The results of these studies and publications can be found at the bottom of the page.

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Abrasions, cuts, and insect bites all have the same mechanism of action. Each of these every-day issues are mediated by TRPV1 and as a result, are all easily combatted by Rescuderm.

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Rescuderm’s applications also include blistering where its rapid action limits tissue damage on top of providing effective treatment of oral surgical procedures (such as common wisdom tooth removal), since it can be safely ingested.

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